A titration is a method that is used to investigate reactions between substances. It can be used to investigate the neutralisation reaction between an acid and a base. Titrations use pipettes and burettes to measure volumes of liquids very accurately. A pipette is used to measure an exact volume of a base to be added to a conical flask. A burette is used to measure the volume of acid that is added in the base in the conical flask. An indicator is added to the conical flask. At the endpoint of the titration, the last drop of acid neutralises the remaining molecules of the base. The indicator changes colour at the end point of netralisation.